Transcriptome sequencing analysis of tibial transverse transport in a rabbit model of diabetic foot ulcers

• Identified 9 significantly differentially expressed miRNAs and 2,667 mRNAs in a rabbit model of diabetic foot ulcers treated with tibial transverse transport. • Constructed a miRNA-mRNA regulatory network comprising 7 miRNAs and 79 target genes, highlighting key regulatory interactions. • Core target genes (BAG3, AKT3, PPP4C, SEC61A1, DNAJC3, USP7, DAD1, SETD7) were identified via protein-protein interaction analysis. • Enriched pathways include metabolic pathways, FoxO signaling, and propanoate metabolism, offering new therapeutic targets for diabetic foot ulcers.