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Protected by Google reCAPTCHA v3.•Privacy•Terms Key Findings in This Report
• MSCs exhibit potent immunomodulatory and multipotent differentiation properties, positioning them as promising therapeutic agents for intestinal diseases.
• MSC-derived exosomes may modulate ZBP1-associated H3K27 acetylation to attenuate intestinal epithelial apoptosis, revealing a novel epigenetic regulatory axis.
• Clinical translation of MSC therapy faces challenges including standardization, delivery optimization, and long-term safety evaluation.
• Tissue engineering applications of MSCs represent cutting-edge advancements for intestinal repair and regeneration.