Key Takeaways & Executive Findings
- •• The article has been retracted due to concerns about figure provenance and data reliability. • The retraction was initiated after authors requested to replace figures, raising integrity issues. • All authors disagree with the retraction, indicating a dispute over the decision. • This retraction highlights the importance of rigorous figure and data verification in scientific publishing.
Abstract
The Editor-in-Chief has retracted this article. The authors of this article subsequently contacted the journal to request to replace components of Figs. 1B, 6E, 6H and 7A. Further investigation raised concerns regarding the provenance of the replacement figures and the rationale behind the need to replace these figures. The Editor-in-Chief therefore no longer has confidence in the reliability of the data reported in this article. Author Yong-lan Wang has stated that all authors disagree with this retraction.
1. Introduction
This article has been retracted by the Editor-in-Chief of Stem Cell Research & Therapy. The retraction follows an investigation into concerns raised after the authors requested to replace components of several figures (Figs. 1B, 6E, 6H, and 7A). The investigation found issues with the provenance of the replacement figures and the rationale for their replacement, leading to a loss of confidence in the reliability of the reported data.
The original article, published in 2020, reported on the role of osteocyte-derived exosomes in promoting periodontal ligament stem cell proliferation and osteogenic differentiation via the miR-181b-5p/PTEN/AKT signaling pathway. The retraction note serves as a formal notice to the scientific community about the withdrawal of this article due to integrity concerns.
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Pei-ying Lv, Peng-fei Gao, Guang-jie Tian, Yan-yan Yang, Fei-fei Mo, Zi-hui Wang, Lu Sun, Ming-jie Kuang, Yong-lan Wang (2026). Retraction Note: Osteocyte-derived exosomes induced by mechanical strain promote human periodontal ligament stem cell proliferation and osteogenic differentiation via the miR-181b-5p/PTEN/AKT signaling pathway. Stem Cell Research & Therapy. https://doi.org/10.1186/s13287-024-04031-5
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Frequently Asked Questions
Why was this article retracted?
The article was retracted because the Editor-in-Chief lost confidence in the reliability of the data after an investigation into concerns about the provenance of replacement figures and the rationale for their replacement.
Who are the authors of the retracted article?
The authors are Pei-ying Lv, Peng-fei Gao, Guang-jie Tian, Yan-yan Yang, Fei-fei Mo, Zi-hui Wang, Lu Sun, Ming-jie Kuang, and Yong-lan Wang.
What was the original article about?
The original article investigated the effects of osteocyte-derived exosomes induced by mechanical strain on human periodontal ligament stem cell proliferation and osteogenic differentiation, focusing on the miR-181b-5p/PTEN/AKT signaling pathway.
Do the authors agree with the retraction?
No, author Yong-lan Wang has stated that all authors disagree with the retraction.
What is the DOI of the retraction note?
The DOI of the retraction note is 10.1186/s13287-024-04031-5.
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