• Annual publications on postmenopausal cognitive impairment have shown a fluctuating upward trend over the past two decades, indicating growing research interest.
• The United States leads in research output, with top institutions including Stanford University, University of Pittsburgh, Harvard Medical School, and University of Illinois.
• Hormonal interventions, particularly estrogen therapy and its long-term safety, remain the central focus, as evidenced by high-frequency and burst keywords.
• Research themes have expanded from single topics like MRI and hormones to broader health issues (psychological, tumor risk, cardiovascular, metabolic, physical activity), with a shift toward non-hormonal intervention strategies.
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