• The number of publications on oxidative stress and osteoporosis has increased significantly from 1999 to 2024, especially after 2011, indicating growing research interest.
• China leads in publication volume but has lower average citations per paper, while the United States shows higher research quality with an average of 74.62 citations per paper.
• Core authors such as Almeida and Manolagas have high influence, and American journals like the Journal of Bone and Mineral Research are central to the field.
• Research hotspots include the interaction mechanisms of oxidative stress and bone metabolism, inflammation, and the development of antioxidant therapies.