Official PDF Translation•Acta Biochimica et Biophysica Sinica

Function and mechanism of action of the TRPV1 channel in the development of triple-negative breast cancer

Authors: Ziling Yan; Haihui Huang; Qianqian Wang; Yanjie Kong; Xia Liu

DOI: 10.3724/abbs.2024068Status: Verified Translated Edition

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Key Findings in This Report

• TRPV1 is highly expressed in triple-negative breast cancer (TNBC) and plays a role in cancer growth, metastasis, apoptosis, and pain. • Both TRPV1 agonists and antagonists exhibit anti-cancer effects, suggesting a complex regulatory mechanism. • TRPV1 may influence immunotherapy outcomes in TNBC, offering potential as a therapeutic target. • This review highlights the need for further research to develop TRPV1-based treatment strategies for TNBC.