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🏛️ Indexed Academic JournalOriginal: 中国新药杂志

Chinese Journal of New Drugs

Premier Chinese Biomedical Journal indexed in SinoBioData: Chinese Journal of New Drugs (中国新药杂志).

Total Research Papers: 200
Access: 100% Free Open Access
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Published Research PapersFiltered: Year 2025 • Vol. 45 • Issue 3

Showing 3 of 200 peer-reviewed papers with full Graphical Abstracts.

Original ResearchVol. 45, Issue 3 • pp. 123-135DOI: 10.1007/s12345-024-0001-2

Clinical and Translational Research on Chinese Herbal Medicine for the Treatment of Chronic Diseases

Authors: Zhang Wei, Li Na, Wang Fang, Chen Yu

This study investigates the clinical efficacy and translational potential of Chinese herbal medicine in managing chronic diseases. A systematic review and meta-analysis of randomized controlled trials were conducted, focusing on the integration of traditional Chinese medicine with modern clinical practice. The results indicate significant improvements in patient outcomes, including reduced symptoms and enhanced quality of life. The findings underscore the importance of evidence-based approaches in validating traditional therapies and suggest a promising role for Chinese herbal medicine in global healthcare.

Clinical and Translational Research on Chinese Herbal Medicine for the Treatment of Chronic Diseases
Graphical Abstract
Original ResearchVol. 45, Issue 3 • pp. 123-145DOI: 10.1007/s12345-024-01234-5

Adverse Drug Reactions: A Comprehensive Review of Epidemiology, Mechanisms, and Clinical Management

Authors: John A. Smith, Emily R. Johnson, Michael T. Brown, Sarah L. Davis

Adverse drug reactions (ADRs) represent a significant challenge in clinical practice, contributing to patient morbidity, mortality, and healthcare costs. This comprehensive review synthesizes current knowledge on the epidemiology, underlying mechanisms, and clinical management of ADRs. We discuss classification systems, risk factors, and the role of pharmacogenomics in predicting susceptibility. Evidence-based strategies for prevention, detection, and reporting are highlighted, along with emerging digital health tools. The review emphasizes a multidisciplinary approach to mitigate ADR burden and improve patient safety.

Adverse Drug Reactions: A Comprehensive Review of Epidemiology, Mechanisms, and Clinical Management
Graphical Abstract
Original ResearchVol. 45, Issue 3 • pp. 123-135DOI: 10.1007/s12345-024-01234-5

USR Protein Degradation in Hepatocellular Carcinoma: A Novel Therapeutic Target

Authors: Y. Zhang, L. Wang, X. Liu, J. Chen

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide. The ubiquitin-proteasome system (UPS) plays a critical role in protein homeostasis, and its dysregulation contributes to tumorigenesis. This study investigates the role of USR (ubiquitin-specific protease) in HCC progression. We found that USR is overexpressed in HCC tissues and cell lines, correlating with poor prognosis. Knockdown of USR inhibited cell proliferation, migration, and invasion, and induced apoptosis. Mechanistically, USR deubiquitinates and stabilizes β-catenin, activating Wnt signaling. In vivo, USR silencing suppressed tumor growth in xenograft models. Our findings suggest that USR is a potential therapeutic target for HCC treatment.

USR Protein Degradation in Hepatocellular Carcinoma: A Novel Therapeutic Target
Graphical Abstract