• TCM significantly reduces serum creatinine and blood urea nitrogen levels in CKD patients, indicating improved renal function.
• TCM increases estimated glomerular filtration rate (eGFR) and reduces proteinuria, suggesting a renoprotective effect.
• The safety profile of TCM appears comparable to conventional treatment, with no significant increase in adverse events.
• Despite positive findings, the evidence is limited by heterogeneity and methodological flaws in existing RCTs, warranting further high-quality research.