Supplemental Experience and Clinical Outcomes in Patients with Advanced Cancer: A Systematic Review and Meta-Analysis

• Supplemental experience significantly improves overall survival and progression-free survival in advanced cancer patients. • Quality of life is enhanced with supplemental experience, with a moderate effect size. • The safety profile of supplemental experience is comparable to standard care, with no significant increase in severe adverse events. • These findings suggest that supplemental experience could be integrated into clinical practice as an adjunctive treatment for advanced cancer.