Official PDF Translation•Stem Cell Research & Therapy

Retraction Note: Secretome of endothelial progenitor cells from stroke patients promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage

Authors: Rodrigo Azevedo Loiola; Miguel García-Gabilondo; Alba Grayston; Paulina Bugno; Agnieszka Kowalska; Sophie Duban-Deweer; Eleonora Rizzi; Johan Hachani; Yasuteru Sano; Fumitaka Shimizu; Takashi Kanda; Caroline Mysiorek; Maciej Piotr Mazurek; Anna Rosell; Fabien Gosselet

DOI: 10.1186/s13287-024-03667-7Status: Verified Translated Edition

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Key Findings in This Report

• The original article has been retracted due to misidentification of endothelial progenitor cells as hCMEC/D3 cell line. • STR genotyping revealed >95% probability of hCMEC/D3, not primary EPCs, invalidating the study's results. • The retraction underscores the critical importance of cell line authentication in stem cell research. • The authors' voluntary investigation and transparency serve as a model for research integrity.