Pharmacoeconomic Evaluation of Pharmacological Treatments for Oral Diseases

• Pharmacoeconomic evaluations reveal that fluoride varnish and sealants are cost-effective for preventing dental caries in high-risk populations. • Systemic antibiotics combined with scaling and root planing demonstrate favorable cost-effectiveness for periodontitis management. • Targeted therapies for oral cancer are cost-effective in specific patient subgroups, emphasizing the need for personalized treatment approaches. • The review highlights significant heterogeneity and methodological variability, underscoring the need for standardized pharmacoeconomic studies in oral health.