Optimization of the Separation Process of the Top Five Cumulative Organs of Solanum Tuberosum Using Response Surface Methodology

• Optimized extraction conditions for Solanum tuberosum organs using RSM, achieving a 12.5% yield and 95.2% purity. • Identified temperature, time, and ethanol concentration as critical factors affecting extraction efficiency. • Demonstrated the effectiveness of Box-Behnken design in modeling and optimizing the separation process. • Provides a scalable and efficient method for industrial extraction of bioactive compounds from Solanum tuberosum.