Minimally Invasive Treatment of Chronic Wounds: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

• Minimally invasive treatments significantly improve wound healing rate by 45% compared to standard care. • Healing time is reduced by an average of 12.3 days with minimally invasive interventions. • Pain scores and infection rates are significantly lower with minimally invasive treatments. • Benefits are consistent across diabetic foot ulcers, venous leg ulcers, and pressure injuries, supporting broad clinical adoption.