• Circadian rhythms significantly influence drug metabolism, efficacy, and toxicity, making medication timing a crucial factor in therapeutic success.
• Chronotherapy has demonstrated improved outcomes in conditions like hypertension, asthma, and cancer when dosing schedules are aligned with biological rhythms.
• Personalized medication timing can enhance treatment effectiveness, reduce adverse events, and improve patient adherence.
• Implementation of chronopharmacology in clinical practice requires robust biomarkers and consideration of individual chronotypes.