Human umbilical cord mesenchymal stem cells enhance liver regeneration and decrease collagen content in fibrosis mice after partial hepatectomy by activating Wnt/β-catenin signaling

• MSC therapy significantly enhances liver function and mitigates liver inflammation after partial hepatectomy in fibrotic livers. • MSCs promote liver regeneration and alleviate liver fibrosis by activating Wnt/β-catenin signaling. • The combination of MSCs with hepatectomy offers a novel therapeutic approach for liver fibrotic diseases. • This study addresses the gap in MSC therapy for impaired liver regeneration in fibrosis context.