Glycosylation in aging and neurodegenerative diseases

• Glycosylation alterations are closely linked to aging and the pathogenesis of neurodegenerative diseases such as Alzheimer's, Parkinson's, and ALS. • Glycosylation profiles hold promise as biomarkers for early detection, prognosis, and monitoring of age-related neurodegenerative conditions. • Understanding glycosylation mechanisms may reveal novel therapeutic targets to mitigate aging and disease progression. • Integrative approaches combining glycosylation research with aging biomarkers can deepen our understanding of the aging process.