• A high-fidelity finite element model of the wrist joint was developed incorporating bones, muscles, tendons, ligaments, interosseous membrane, and cartilage, overcoming limitations of previous models that lacked soft tissue components.
• The model comprised 759,191 elements and 245,510 nodes, and was validated by comparing stress distribution at the radiocarpal joint under axial compression with cadaveric studies.
• The inclusion of forearm muscles with their origins, insertions, and muscle-bone contacts enhanced the realism and accuracy of the model for biomechanical simulations.
• This comprehensive model provides a valuable tool for future biomechanical research on the wrist, potentially aiding in clinical applications such as implant design and surgical planning.