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Official PDF TranslationChinese Journal of New Drugs

Electrochemical Detection of Neurotransmitters Using a Novel AL.CY.cL-Based Sensor: A Study on Sensitivity and Selectivity

Authors: ZHANG Wei; LI Ming; WANG Fang; LIU Yang

DOI: pub_80__articleID_253Status: Verified Translated Edition
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Key Findings in This Report

• • Detection limits of 0.5 μM for dopamine and 0.8 μM for serotonin were achieved, enabling quantification of basal neurotransmitter levels in microdialysis samples. • • The sensor exhibited a linear range from 1 μM to 100 μM (R² > 0.99), covering the physiological and pathological concentration ranges for neurological studies. • • Reproducibility was excellent with RSD < 5% across 10 consecutive measurements, ensuring reliable batch-to-batch consistency for clinical or industrial deployment. • • Stability was maintained over 30 days of storage, with only a 5% signal decay, supporting long-term use in continuous monitoring applications.