• Fascia iliaca compartment block provides superior postoperative analgesia compared with femoral nerve block in femoral neck and intertrochanteric fractures, but not in subtrochanteric fractures.
• Fascia iliaca compartment block significantly reduces inflammatory and stress responses, as well as morphine consumption, and shortens time to first ambulation and hospital stay.
• Block type, fracture type, age ≥75 years, and ASA grade III are independent predictors of analgesic effect.
• A nomogram prediction model was developed and validated to guide individualized analgesic strategy selection.
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