• Herbal extracts significantly reduce the duration of herpes simplex lesions by approximately 1.2 days compared to control treatments.
• The recurrence rate of HSV infections is reduced by 38% with the use of herbal extracts, indicating a potential benefit for long-term management.
• No significant increase in adverse events was observed, suggesting that herbal extracts are a safe adjunctive therapy for HSV.
• The therapeutic effect is more pronounced in patients with recurrent infections and when treatment duration exceeds 7 days, highlighting the importance of treatment adherence.