Cost-Effectiveness Analysis of Nutritional Interventions for Chronic Disease Prevention

• Mediterranean and plant-based diets are cost-effective for preventing cardiovascular disease and type 2 diabetes, with ICERs below $50,000/QALY. • Nutritional interventions yield net cost savings in high-risk populations by reducing hospitalizations and medication use. • Economic modeling demonstrates long-term health benefits and cost-effectiveness across diverse willingness-to-pay thresholds. • Findings support policy and clinical integration of nutritional counseling and food-based interventions for chronic disease prevention.