Official PDF Translation•Stem Cell Research & Therapy
Correction: Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models
Authors: Mathew Blurton-Jones; Brian Spencer; Sara Michael; Nicholas A. Castello; Andranik A. Agazaryan; Joy L. Davis; Franz-Josef Müller; Jeanne F. Loring; Eliezer Masliah; Frank M. LaFerla
• This correction addresses an artifact in Fig. 6H of the original article, ensuring accurate representation of data.
• The corrected image clarifies the effects of sNEP-NSC transplantation on amyloid pathology in a second transgenic AD model.
• The study underscores the potential of genetically modified neural stem cells expressing neprilysin as a therapeutic strategy for Alzheimer's disease.
• The correction maintains the integrity of the original findings, which showed reduced plaque pathology and synaptotoxicity.