• A novel microfluidic sensor integrates impedance spectroscopy with microelectrode arrays for real-time ion concentration detection.
• The sensor exhibits a linear response from 0.1 mM to 100 mM with a detection limit of 0.1 mM and response time under 5 seconds.
• The miniaturized design enables integration into lab-on-a-chip systems, reducing sample volume to microliters.
• The method demonstrates high reproducibility and stability, making it suitable for point-of-care diagnostics and environmental monitoring.
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