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Official PDF TranslationStem Cell Research & Therapy

Comment on "Effectiveness and safety of stem cell therapy for diabetic foot: a meta-analysis update"

Authors: Yan Bai; Fan Zhang

DOI: 10.1186/s13287-023-03608-wStatus: Verified Translated Edition
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Key Findings in This Report

• The commentary identifies critical methodological flaws in a published meta-analysis on stem cell therapy for diabetic foot, including misinterpretation of forest plot results due to inadequate RevMan knowledge. • It emphasizes the necessity of applying continuity correction for zero-event trials to ensure accurate pooled estimates in meta-analyses. • The authors advocate for improved presentation of forest plots to enhance readability and interpretability in scientific publications. • Registration of systematic review protocols with PROSPERO or INPLASY is strongly recommended to increase transparency and reduce bias.
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