Bibliometric and visualization analysis of the mechanism of osteogenic factors and neurotransmitters in the bone-brain axis

• Publication volume on the bone-brain axis increased significantly from 2015 to 2024, with the USA and China leading in research output. • Core research themes include bone marrow, stem cells, osteoporosis, and neuroinflammation, with emerging focus on extracellular vesicles and Alzheimer's disease. • The journal Bone is the primary publication platform, while PLOS ONE exhibits high citation impact in this field. • Future research should prioritize understanding molecular mechanisms and fostering international collaboration to translate findings into clinical practice.