• Global research output on Parkinson's disease animal models has shown a fluctuating upward trend, with China and the USA contributing 52.6% of publications.
• Key pathological mechanisms studied include neuroinflammation, gut microbiota, oxidative stress, mitochondrial dysfunction, and α-synuclein; ferroptosis is an emerging topic in domestic research.
• Traditional Chinese medicine is highly emphasized in domestic research, and interdisciplinary collaboration holds significant potential.
• Novel therapeutic strategies such as gene therapy and stem cell transplantation are being explored, with future integration of gene editing, AI, and brain-computer interfaces anticipated.