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Official PDF Translation•Chinese Journal of Tissue Engineering Research

Advantages and potential of cell-derived exosomes in oral tissue regeneration

Authors: Li Jiapeng; ZuleinaĀ·Abula; Jia Qianqian; NigareĀ·Yunusijiang; Sun Jiaqi; Zhao Jin; Wu Zeyu

DOI: 10.12307/2026.21356Status: Verified Translated Edition
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Key Findings in This Report

• Exosomes offer lower immunogenicity and no tumorigenic risk compared to stem cells, making them a safer alternative for oral tissue regeneration. • Exosomes demonstrate significant efficacy in regenerating dental pulp, periodontal tissues, craniofacial bone, salivary glands, nerves, and skin. • Engineering strategies such as preconditioning, isolation, and targeted modification can enhance exosome therapeutic potential. • Future research should focus on optimizing exosome production and clinical translation to overcome current limitations.