Official PDF Translation•Stem Cell Research & Therapy
Advances in the clinical application of mesenchymal stem cells for neurological disorders
Authors: Mohammad Chand Jamali; Alaa Shafie; Ali Jaber Alqahtani; Rithab Ibrahim Al-Samawi; Hanan Mesfer Alyami; Amal Adnan Ashour; Mohammed Fareed Felemban; Nasrin Mansuri; Faris J. Tayeb; Irshad Ahmad; Mustafa Mudhafar; Salah Ahmed Sheweita
• MSC-based therapies show a favorable safety profile across neurological disorders, but clinical efficacy remains inconsistent.
• Variability in MSC sources, manufacturing, delivery routes, and dosing contributes to heterogeneous outcomes.
• Standardization of protocols and biomarker-driven patient selection are critical for advancing MSC therapies.
• Future progress requires large-scale randomized trials to establish clinical effectiveness.