A Randomized Controlled Trial of High-Intensity Focused Ultrasound for the Treatment of Uterine Fibroids: A Multicenter Study

• HIFU ablation achieves significant fibroid volume reduction (45.2% at 6 months) with fewer adverse events compared to myomectomy. • Symptom severity and quality of life improvements are comparable between HIFU and surgery. • HIFU is a non-invasive option with shorter recovery time and lower complication rates. • Patient selection and tumor characteristics are critical for optimal HIFU outcomes.