A Novel Approach for the Detection and Quantification of Impurities in Pharmaceutical Compounds Using Advanced Chromatographic Techniques

• Developed a rapid and sensitive UHPLC-MS/MS method for impurity profiling in pharmaceuticals. • Achieved detection limits as low as 0.01% for targeted impurities, meeting regulatory requirements. • Successfully identified and quantified impurities in real drug samples, demonstrating practical applicability. • The method reduces analysis time by 50% compared to conventional HPLC methods, enhancing laboratory efficiency.