🧬 SinoBioData Academic Portal
🏛️ Indexed Academic JournalOriginal: 中国新药杂志

Chinese Journal of New Drugs

Premier Chinese Biomedical Journal indexed in SinoBioData: Chinese Journal of New Drugs (中国新药杂志).

Total Research Papers: 200
Access: 100% Free Open Access
Browse by Publication Year & VolumeReset All Filters ✕

Published Research PapersFiltered: Year 2025 • Vol. 49 • Issue 1

Showing 1 of 200 peer-reviewed papers with full Graphical Abstracts.

Original ResearchVol. 49, Issue 1 • pp. 1-12DOI: 10.1007/s40846-024-00867-1

Development of a Renal Function Assessment and Monitoring System Using Machine Learning and Cloud Computing

Authors: Y. Zhang, L. Wang, H. Li, J. Chen

Chronic kidney disease (CKD) is a global health burden, and early detection is crucial for effective management. This study presents a novel renal function assessment and monitoring system that integrates machine learning algorithms with cloud computing to enable real-time, non-invasive monitoring of renal function. The system utilizes a multi-modal approach, combining clinical biomarkers, patient demographics, and continuous physiological data from wearable sensors. A gradient boosting machine (GBM) model was trained on a large retrospective cohort (n=12,000) and validated on a prospective cohort (n=1,500), achieving an AUC of 0.94 for detecting early-stage CKD. The system also incorporates a cloud-based dashboard for remote monitoring and alerts, facilitating timely interventions. Key innovations include the use of explainable AI (XAI) to provide interpretable predictions, and a federated learning framework to ensure data privacy. The system demonstrated high accuracy, scalability, and usability in clinical settings, suggesting its potential to transform CKD management by enabling proactive, personalized care.

Development of a Renal Function Assessment and Monitoring System Using Machine Learning and Cloud Computing
Graphical Abstract