Visualization Analysis of Knowledge Graph on Regulation of Mitochondrial Reactive Oxygen Species by Traditional Chinese Medicine Based on CiteSpace and VOSviewer

• • A total of 1,026 Chinese and 649 English articles were analyzed, revealing a sustained growth trend in annual publication output; this volume indicates robust research activity but also signals potential redundancy in basic antioxidant mechanism studies, necessitating a shift toward precision-targeted investigations. • • China dominates the field with core institutions such as Heilongjiang University of Chinese Medicine, Henan University of Chinese Medicine, and Guangxi University of Chinese Medicine; however, the lack of dense domestic and international collaboration networks impedes cross-validation of mechanistic findings and slows clinical translation. • • Keyword burst analysis identifies a decisive frontier shift from basic antioxidant mechanisms toward network pharmacology, molecular docking, and ferroptosis; this transition reflects the field's maturation from descriptive oxidative stress modulation to actionable, target-specific interventions with higher industrial and clinical relevance. • • The most productive journals are Chinese Journal of Experimental Traditional Medical Formulae and Journal of Ethnopharmacology, providing clear publication channels; researchers targeting high-impact dissemination should align their mechanistic studies with the scope of these journals to maximize visibility and citation potential.