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Verified CAS / Academic Author2 Decoded Studies

Prof. Ruichen Zhao

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Co-Affiliations:Acta Biochimica et Biophysica Sinica

Research Publications & English Decoded Briefs

Showing 2 publications
Acta Biochimica et Biophysica Sinica•2025•DOI: 10.3724/abbs.2025233

Caveolin-1-deficient fibroblasts promote migration, invasion, and stemness by activating the TGF-β/Smad signaling pathway in breast cancer cells

This is a corrigendum to the article 'Caveolin-1-deficient fibroblasts promote migration, invasion, and stemness by activating the TGF-β/Smad signaling pathway in breast cancer cells' published in Acta Biochim Biophys Sin 54: 1587–1598. The authors identified inaccuracies in the preparation of several figures (Figure 2D, 4A, and 5A) and have replaced them with corrected versions. The errors are strictly confined to figure presentation and do not impact the underlying data, statistical analysis, or main conclusions. The authors apologize for the oversight.

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Acta Biochimica et Biophysica Sinica•2025•DOI: 10.3724/abbs.2025233

Corrigendum to 'Caveolin-1-deficient fibroblasts promote migration, invasion, and stemness by activating the TGF-β/Smad signaling pathway in breast cancer cells'

This corrigendum addresses inaccuracies in three figure panels from the original article (Acta Biochim Biophys Sin 54: 1587–1598, doi: 10.3724/abbs.2022150). The authors identified that Figure 2D was mislabeled during preparation, Figure 4A contained an incorrect image due to a processing error, and Figure 5A was mistakenly replaced during final compilation. Corrected versions of these panels are provided. The authors confirm that these errors are confined to figure presentation and do not affect the underlying data, statistical analyses, or the main conclusions of the study. The original research demonstrated that caveolin-1 (CAV-1)-deficient fibroblasts promote migration, invasion, and stemness in breast cancer cells (BCCs) via activation of the TGF-β/Smad signaling pathway. Key experimental methods included Western blot for CAV-1 expression, scratch wound healing assays for migration, Transwell assays for migration and invasion, immunofluorescence and ELISA for TGF-β1 detection, and Western blot for EMT/stemness markers. Statistical significance was set at P < 0.05. This corrigendum ensures the accuracy of the scientific record and maintains the integrity of the reported findings.

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